TYMS

OMIMHGNC

Synonym(s): Tsase, TMS, HsT422, TS

Locus: 18p11.32

Tests

Test Type
Molecular (6)
Multi-Gene Panel (5)
Multi-Method Panel (2)
Test Method
Del/Dup (CNV) (2)
Sequencing, Capillary (Sanger) (4)
Genotyping (Microarray, Beads, etc.) (2)
Sequencing, Next Gen (2)
Lab Location
Spain(2)
Portugal(1)
USA(2)
Germany(1)
 
Susceptibility to Drugs (5-Fluoruracil), Sequencing DPYD Gene and Genotype (2R/2R,2R/3R,3R/3R) TYMS Gene
method(s): ◦ Genotyping (Microarray, Beads, etc.) ◦ Sequencing, Capillary (Sanger) 
Reference Laboratory Genetics - Hospitalet de Llobregat, Spain
5-fluorouracil toxicity (2 alleles on MTHFR, 1 allele on TYMS and 1 allele on DPYD genes)
method(s): ◦ Sequencing, Capillary (Sanger) 
CGC Genetics - Porto, Portugal
Toxicity to Fluoropyrimidines: DPYD gene and TYMS (2R / 2R, 2R / 3R o 3R / 3R) gene sequence analysis and genotype determination
method(s): ◦ Sequencing, Capillary (Sanger) 
GENETAQ, Molecular Genetics Centre - Malaga, Spain
TAT: 4-6 weeks
price: contact lab
Somatic Tumor Panel
method(s): ◦ Del/Dup (CNV) ◦ Sequencing, Next Gen 
CeGaT GmbH - Tübingen, Germany
5-Fluorouracil (5-FU) Toxicity and Chemotherapeutic Response, 5 Mutations
method(s): ◦ Genotyping (Microarray, Beads, etc.) 
ARUP Laboratories, Molecular Genetics Laboratory - Salt Lake City, UT, USA
TAT: 4-5 Weeks
price: contact lab
TYMS
method(s): ◦ Sequencing, Next Gen ◦ Sequencing, Capillary (Sanger) ◦ Del/Dup (CNV) 
Fulgent Diagnostics - Temple City, CA, USA