SERPING1

OMIMHGNC

Synonym(s): C1IN, C1-INH, HAE1, HAE2, C1NH

Locus: 11q12.1

Protein: Serine/cysteine proteinase inhibitor clade G member 1 splice variant 2

 

Disorders

Tests

Test Type
Molecular (29)
Multi-Gene Panel (11)
Multi-Method Panel (10)
Test Method
Del/Dup (CNV) (13)
Mutation Scanning of Entire Coding Region (2)
Sequencing, Capillary (Sanger) (13)
Sequencing, Next Gen (12)
Prenatal/Carrier
Prenatal (7)
Carrier (9)
Lab Location
Netherlands(1)
USA(9)
Spain(4)
Portugal(5)
Slovakia(1)
Germany(5)
Czech Republic(1)
Finland(2)
Austria(1)
 
TAT: 4-8 weeks
price: $635.00
Analysis SERPING1 (C1NH) gene (Hereditary Angioedema types I and II)
method(s): ◦ Del/Dup (CNV) ◦ Sequencing, Capillary (Sanger) 
Academic Medical Centre, University of Amsterdam, DNA Diagnostics Laboratory - Amsterdam, Netherlands
TAT: 2-4 weeks
price: contact lab
Hereditary Angioedema Test
method(s): ◦ Del/Dup (CNV) ◦ Sequencing, Next Gen 
Ambry Genetics Corp, Ambry Genetics - Aliso Viejo, CA, USA
Hereditary Angioedema Test
method(s): ◦ Mutation Scanning of Entire Coding Region 
Centre for Cardiovascular Surgery and Transplantation, Molecular Genetics Laboratory - Brno, Czech Republic
Hereditary Angioedema
method(s): ◦ Sequencing, Capillary (Sanger) ◦ Del/Dup (CNV) 
MVZ Dortmund Dr. Eberhard and Partner - Dortmund, Germany
TAT: 6-7 weeks
price: contact lab
Sanger sequencing of the SERPING1 gene
method(s): ◦ Mutation Scanning of Entire Coding Region ◦ Sequencing, Capillary (Sanger) 
Sistemas Genomicos, Medical Genetics Unit - Paterna, Spain
TAT: 3-4 weeks
price: contact lab
SERPING1 (C1INH) Del/Dup
method(s): ◦ Del/Dup (CNV) 
GeneDx - Gaithersburg, MD, USA
TAT: 5-6 weeks
price: contact lab
SERPING1 (C1INH) Gene Sequencing and Del/Dup
method(s): ◦ Sequencing, Capillary (Sanger) ◦ Del/Dup (CNV) 
GeneDx - Gaithersburg, MD, USA
Primary Immunodeficiency Gene Panel
method(s): ◦ Sequencing, Next Gen 
All Children's Hospital, Histocompatibility and Immunogenetics Laboratory - St. Petersburg, FL, USA
Hereditary Angioedema Types 1 and 2, Sequencing SERPING1 Gene
method(s): ◦ Sequencing, Capillary (Sanger) 
Reference Laboratory Genetics - Hospitalet de Llobregat, Spain
Hereditary angioedema type 1 (sequence analysis of SERPING1 gene)
method(s): ◦ Sequencing, Capillary (Sanger) 
CGC Genetics - Porto, Portugal
SERPING1
method(s): ◦ Sequencing, Capillary (Sanger) 
St. Elisabeth Cancer Institute, Department of Clinical Genetics - Bratislava, Slovakia
Angioedema Type 1 and 2, Hereditary: SERPING1 gene sequence analysis
method(s): ◦ Sequencing, Capillary (Sanger) 
GENETAQ, Molecular Genetics Centre - Malaga, Spain
Hereditary Angioedema Types 1 and 2, Deletions-Duplications (MLPA) SERPING1 Gene
method(s): ◦ Del/Dup (CNV) 
Reference Laboratory Genetics - Hospitalet de Llobregat, Spain
TAT: 7-10 days
price: contact lab
NewbornDx
method(s): ◦ Sequencing, Next Gen 
Parabase Genomics - Boston, MA, USA
Hereditary angioedema type 1 (deletion/duplication analysis of SERPING1 gene)
method(s): ◦ Del/Dup (CNV) 
CGC Genetics - Porto, Portugal
TAT: 4-6 weeks
price: contact lab
Vascular and lymphatic disorders Panel
method(s): ◦ Sequencing, Next Gen 
CeGaT GmbH - Tübingen, Germany
TAT: 2-4 weeks
price: contact lab
Single gene testing SERPING1
method(s): ◦ Del/Dup (CNV) ◦ Sequencing, Capillary (Sanger) 
CeGaT GmbH - Tübingen, Germany
TAT: 4-6 weeks
price: contact lab
Complement Deficiencies Panel
method(s): ◦ Sequencing, Next Gen 
CeGaT GmbH - Tübingen, Germany
TAT: 4-5 Weeks
price: contact lab
SERPING1
method(s): ◦ Sequencing, Next Gen ◦ Sequencing, Capillary (Sanger) ◦ Del/Dup (CNV) 
Fulgent Diagnostics - Temple City, CA, USA
Complement deficiencies � all subtypes (NGS panel of 33 genes)
method(s): ◦ Sequencing, Next Gen 
CGC Genetics - Porto, Portugal
Complement deficiencies � Low susceptibility to infections: SLE-like syndrome, atypical hemolytic uremic syndrome and others (NGS panel of 19 genes)
method(s): ◦ Sequencing, Next Gen 
CGC Genetics - Porto, Portugal
Complement deficiencies - low susceptibility to infections: others (NGS panel of 2 genes)
method(s): ◦ Sequencing, Next Gen 
CGC Genetics - Porto, Portugal
TAT: 3-4 weeks
price: contact lab
Primary Immunodeficiency Panel
method(s): ◦ Del/Dup (CNV) ◦ Sequencing, Next Gen 
Blueprint Genetics - Helsinki, Finland
TAT: 3-4 weeks
price: contact lab
Complement System Disorder Panel
method(s): ◦ Del/Dup (CNV) ◦ Sequencing, Next Gen 
Blueprint Genetics - Helsinki, Finland
TAT: 3-4 weeks
price: $690.00
Hereditary Angioedema via the SERPING1 /C1NH Gene
method(s): ◦ Del/Dup (CNV) 
PreventionGenetics (Prevention Genetics), Clinical DNA Testing and DNA Banking - Marshfield, WI, USA
TAT: 2-3 weeks
price: $750.00
Hereditary Angioedema via the SERPING1 /C1NH Gene
method(s): ◦ Sequencing, Capillary (Sanger) 
PreventionGenetics (Prevention Genetics), Clinical DNA Testing and DNA Banking - Marshfield, WI, USA
Angioedema (Angioödem)
method(s): ◦ Sequencing, Capillary (Sanger) 
Praxis fuer Humangenetik Wien - Vienna, Austria
TAT: ~2 weeks
price: contact lab
Angioedema, hereditary
method(s): ◦ Sequencing, Capillary (Sanger) ◦ Del/Dup (CNV) 
Centogene AG, Rare Disease Company - Rostock, Germany
TAT: 4-6 weeks
price: contact lab
Abdominal Pain Spotlight Panel
method(s): ◦ Sequencing, Next Gen 
Courtagen Life Sciences, Courtagen Diagnostics Laboratory - Woburn, MA, USA