KMT2A

OMIMHGNC

Synonym(s): TRX1, HRX, ALL-1, HTRX1, CXXC7, MLL1A, MLL

Locus: 11q23.3

Protein: Histone-lysine N-methyltransferase MLL

 

Disorders

Tests

Test Type
Molecular (17)
Cytogenetic (2)
Multi-Gene Panel (7)
Multi-Method Panel (4)
Test Method
Del/Dup (CNV) (6)
FISH-Interphase (2)
Sequencing, Capillary (Sanger) (5)
Genotyping (Microarray, Beads, etc.) (1)
Sequencing, Next Gen (10)
Prenatal/Carrier
Prenatal (9)
Carrier (9)
Lab Location
USA(8)
Spain(3)
Portugal(2)
Germany(6)
 
TAT: 4 weeks
price: contact lab
KMT2A (MLL) sequencing
method(s): ◦ Sequencing, Next Gen 
University of Chicago, Genetic Services Laboratory - Chicago, IL, USA
TAT: 4 weeks
price: contact lab
KMT2A (MLL) deletion/duplication
method(s): ◦ Del/Dup (CNV) 
University of Chicago, Genetic Services Laboratory - Chicago, IL, USA
Wiedemann-Steiner Syndrome , Sequencing KMT2A Gene
method(s): ◦ Sequencing, Capillary (Sanger) 
Reference Laboratory Genetics - Hospitalet de Llobregat, Spain
TAT: 3 weeks
price: contact lab
Hematopoietic Disorders Gene Set
method(s): ◦ Sequencing, Next Gen 
Genomics and Pathology Services, Washington University - St. Louis, MO, USA
TAT: 4-6 weeks
price: contact lab
Somatic Tumor Panel
method(s): ◦ Del/Dup (CNV) ◦ Sequencing, Next Gen 
CeGaT GmbH - Tübingen, Germany
Acute myelogenous leukemia (detection of mutations PTD on MLL gene)
method(s): ◦ Genotyping (Microarray, Beads, etc.) 
CGC Genetics - Porto, Portugal
Wiedemann-Steiner syndrome (sequence analysis of KMT2A gene)
method(s): ◦ Sequencing, Next Gen 
CGC Genetics - Porto, Portugal
TAT: 2-3 days
price: contact lab
11q23 MLL rearragements
method(s): ◦ FISH-Interphase 
Cidegen, SL - Salamanca, Spain
TAT: 2-4 weeks
price: contact lab
Single gene testing KMT2A
method(s): ◦ Sequencing, Capillary (Sanger) 
CeGaT GmbH - Tübingen, Germany
TAT: 1 week
price: contact lab
11q23 KMT2A (MLL)
method(s): ◦ FISH-Interphase 
Empire Genomics - Buffalo, NY, USA
TAT: 4-5 Weeks
price: contact lab
KMT2A
method(s): ◦ Sequencing, Next Gen ◦ Sequencing, Capillary (Sanger) ◦ Del/Dup (CNV) 
Fulgent Diagnostics - Temple City, CA, USA
TAT: 3-5 weeks
price: contact lab
KMT2A
method(s): ◦ Sequencing, Capillary (Sanger) 
MGZ München, Medizinisch Genetisches Zentrum München - München, Germany
TAT: 3-5 weeks
price: $990.00
Cornelia de Lange Syndrome and Wiedemann-Steiner Syndrome via the KMT2A Gene
method(s): ◦ Sequencing, Next Gen 
PreventionGenetics (Prevention Genetics), Clinical DNA Testing and DNA Banking - Marshfield, WI, USA
TAT: 3-5 weeks
price: $1,790.00
Cornelia de Lange Syndrome Sequencing Panel
method(s): ◦ Sequencing, Next Gen 
PreventionGenetics (Prevention Genetics), Clinical DNA Testing and DNA Banking - Marshfield, WI, USA
TAT: ~2 weeks
price: contact lab
Wiedemann-Steiner syndrome
method(s): ◦ Sequencing, Capillary (Sanger) 
Centogene AG, Rare Disease Company - Rostock, Germany
Myelodysplastic Syndromes, Panel Deletions-Duplications (MLPA)
method(s): ◦ Del/Dup (CNV) 
Reference Laboratory Genetics - Hospitalet de Llobregat, Spain
TAT: 4-5 weeks
price: contact lab
Cornelia de Lange syndrome panel
method(s): ◦ Del/Dup (CNV) ◦ Sequencing, Next Gen 
Centogene AG, Rare Disease Company - Rostock, Germany
TAT: 3-5 weeks
price: $2,290.00
Cornelia de Lange Syndrome and Cornelia de Lange Syndrome-Related Disorders Sequencing Panel
method(s): ◦ Sequencing, Next Gen 
PreventionGenetics (Prevention Genetics), Clinical DNA Testing and DNA Banking - Marshfield, WI, USA
Mental Retardation - different panels
method(s): ◦ Sequencing, Next Gen ◦ Del/Dup (CNV) 
Cologne University, Institute of Human Genetics - Cologne, Germany