JAK2

OMIMHGNC

Synonym(s): JTK10

Locus: 9p24.1

Protein: Janus kinase 2

 

Disorders

Tests

Test Type
Molecular (38)
Cytogenetic (2)
Multi-Gene Panel (23)
Multi-Method Panel (7)
Test Method
Del/Dup (CNV) (7)
Multicolor FISH (M-FISH) / Spectral Karotyping (tm) (SKY (tm)) (2)
Mutation Scanning of Select Exons (3)
Mutation Scanning of Entire Coding Region (3)
Sequencing, Capillary (Sanger) (11)
Genotyping (Microarray, Beads, etc.) (2)
Sequencing, Next Gen (22)
Prenatal/Carrier
Prenatal (2)
Carrier (12)
Lab Location
USA(11)
Turkey(2)
Spain(11)
Germany(4)
Poland(1)
Portugal(2)
Australia(1)
Greece(1)
Austria(3)
Canada(2)
 
Polycythemia Vera Test (the JAK2 gene - the most common mutation)
method(s): ◦ Sequencing, Capillary (Sanger) 
GENESIS Center for Medical Genetics, Laboratory of Molecular Genetics - Poznan, Poland
Analysis of Juvenile Myelomonocytic Leukemia; JMML
method(s): ◦ Multicolor FISH (M-FISH) / Spectral Karotyping (tm) (SKY (tm)) ◦ Sequencing, Next Gen ◦ Sequencing, Capillary (Sanger) 
Center for Human Genetics and Laboratory Medicine Martinsried, Molecular Genetics - Martinsried, Germany
Polycythemia Vera, Mutation (V617F) JAK2 Gene Whole Blood
method(s): ◦ Mutation Scanning of Entire Coding Region 
Reference Laboratory Genetics - Hospitalet de Llobregat, Spain
Polycythemia Vera, Mutation (V617F) JAK2 Gene Bone Marrow
method(s): ◦ Mutation Scanning of Entire Coding Region 
Reference Laboratory Genetics - Hospitalet de Llobregat, Spain
Polycythemia Vera, Sequencing Exon 12 JAK2 Gene Bone Marrow
method(s): ◦ Mutation Scanning of Select Exons 
Reference Laboratory Genetics - Hospitalet de Llobregat, Spain
Congenital Amegakaryocytic Thrombocytopenia , Screening Mutations MPL and JAK2 Genes
method(s): ◦ Mutation Scanning of Entire Coding Region 
Reference Laboratory Genetics - Hospitalet de Llobregat, Spain
Polycythemia Vera, Sequencing Exon 12 JAK2 Gene Whole Blood
method(s): ◦ Mutation Scanning of Select Exons 
Reference Laboratory Genetics - Hospitalet de Llobregat, Spain
JAK2 gene (V617F mutation)
method(s): ◦ Genotyping (Microarray, Beads, etc.) 
CGC Genetics - Porto, Portugal
JAK2-Related Budd-Chiari Syndrome Test
method(s): ◦ Sequencing, Capillary (Sanger) 
Burc Molecular Genetics Laboratory - Istanbul, Turkey
JAK2 Related Polycythemia Vera
method(s): ◦ Del/Dup (CNV) ◦ Sequencing, Capillary (Sanger) 
L.E.S. Mikrogen Genetic Diagnosis Center - Ankara, Turkey
TAT: 2-3 weeks
price: contact lab
NGS HemeOnc Panel
method(s): ◦ Sequencing, Next Gen 
Diagnostic Labs at BloodCenter of Wisconsin - Milwaukee, WI, USA
TAT: 1 week
price: contact lab
JAK2 V617F Mutation Analysis
method(s): ◦ Genotyping (Microarray, Beads, etc.) 
Diagnostic Labs at BloodCenter of Wisconsin - Milwaukee, WI, USA
TAT: 1-2 weeks
price: contact lab
JAK2 Exon 12 Mutation Analysis
method(s): ◦ Sequencing, Capillary (Sanger) 
Diagnostic Labs at BloodCenter of Wisconsin - Milwaukee, WI, USA
JAK2 V617F Mutation Analysis
method(s): ◦ Mutation Scanning of Select Exons 
Cidegen, SL - Salamanca, Spain
TAT: 1-2 weeks
price: contact lab
Targeted Somatic Cancer Panel Sequencing (TSP50)
method(s): ◦ Sequencing, Next Gen 
Genomics for Life APA 1164 - Herston, Queensland, Australia
TAT: 2-3 weeks
price: contact lab
Solid Tumor Gene Set
method(s): ◦ Sequencing, Next Gen 
Genomics and Pathology Services, Washington University - St. Louis, MO, USA
TAT: 2-3 weeks
price: contact lab
Hematopoietic Disorders Gene Set
method(s): ◦ Sequencing, Next Gen 
Genomics and Pathology Services, Washington University - St. Louis, MO, USA
TAT: 4-6 weeks
price: contact lab
Somatic Tumor Panel
method(s): ◦ Sequencing, Next Gen 
CeGaT GmbH - Tübingen, Germany
JAK2 gene (mutations on exon 12)
method(s): ◦ Sequencing, Capillary (Sanger) 
CGC Genetics - Porto, Portugal
TAT: 2-4 weeks
price: contact lab
Single gene testing JAK2
method(s): ◦ Del/Dup (CNV) ◦ Sequencing, Capillary (Sanger) 
CeGaT GmbH - Tübingen, Germany
Com.Pl.i.t. DX 54 genes - Comprehensive Panel for Individualized Cancer Threatment
method(s): ◦ Del/Dup (CNV) ◦ Multicolor FISH (M-FISH) / Spectral Karotyping (tm) (SKY (tm)) ◦ Sequencing, Capillary (Sanger) ◦ Sequencing, Next Gen 
GeneKor Medical S.A. - Athens, Greece
TAT: ~2 weeks
price: contact lab
Hematologic Malignancy Mutation Panel
method(s): ◦ Sequencing, Next Gen 
Baylor Miraca Genetics Laboratories - Houston, TX, USA
OnkoSight Myeloid Disorders Panel
method(s): ◦ Sequencing, Next Gen 
GenPath - Elmwood Park, NJ, USA
OnkoSight MDS Panel
method(s): ◦ Sequencing, Next Gen 
GenPath - Elmwood Park, NJ, USA
OnkoSight MPN Panel
method(s): ◦ Sequencing, Next Gen 
GenPath - Elmwood Park, NJ, USA
TAT: 4-5 Weeks
price: contact lab
JAK2
method(s): ◦ Sequencing, Next Gen ◦ Sequencing, Capillary (Sanger) ◦ Del/Dup (CNV) 
Fulgent Diagnostics - Temple City, CA, USA
Myelofibrosis NGS panel
method(s): ◦ Del/Dup (CNV) ◦ Sequencing, Capillary (Sanger) ◦ Sequencing, Next Gen 
Fulgent Diagnostics - Temple City, CA, USA
Bone Marrow Failure Related Disorders, Panel Massive Sequencing (NGS) 61 Genes
method(s): ◦ Sequencing, Next Gen 
Reference Laboratory Genetics - Hospitalet de Llobregat, Spain
Thrombocytopenia and Related Disorders, Panel Massive Sequencing (NGS) 15 Genes
method(s): ◦ Sequencing, Next Gen 
Reference Laboratory Genetics - Hospitalet de Llobregat, Spain
Erythrocytosis, familial/ Polycythemia (Polyzythämie/ Erythrozytose)
method(s): ◦ Sequencing, Next Gen 
Praxis fuer Humangenetik Wien - Vienna, Austria
Budd-Chiari syndrome (Budd-Chiari Syndrom)
method(s): ◦ Sequencing, Next Gen 
Praxis fuer Humangenetik Wien - Vienna, Austria
Somatic Myelofibrosis, Panel Massive Sequencing (NGS) 4 Genes
method(s): ◦ Sequencing, Next Gen 
Reference Laboratory Genetics - Hospitalet de Llobregat, Spain
Myelodysplastic Syndromes, Panel Deletions-Duplications (MLPA)
method(s): ◦ Del/Dup (CNV) 
Reference Laboratory Genetics - Hospitalet de Llobregat, Spain
Acute Myeloid Leukemia (Susceptibility to), Panel Massive Sequencing (NGS) 21 Genes
method(s): ◦ Sequencing, Next Gen 
Reference Laboratory Genetics - Hospitalet de Llobregat, Spain
Erythrocytosis (Erythrozytosis)
method(s): ◦ Sequencing, Next Gen 
Praxis fuer Humangenetik Wien - Vienna, Austria
CEN4GEN Hematological malignancies (somatic genetic testing): Sequencing Panel
method(s): ◦ Sequencing, Next Gen 
CEN4GEN Institute for Genomics and Molecular Diagnostics - Edmonton, Canada
CEN4GEN Comprehensive targeted oncogene tumor mutation screen (somatic genetic testing): Sequencing Panel
method(s): ◦ Sequencing, Next Gen 
CEN4GEN Institute for Genomics and Molecular Diagnostics - Edmonton, Canada
TAT: ~2 weeks
price: contact lab
Thrombocytosis, familial, JAK2 related
method(s): ◦ Sequencing, Capillary (Sanger) ◦ Del/Dup (CNV) 
Centogene AG, Rare Disease Company - Rostock, Germany