IRAK4

OMIMHGNC

Synonym(s): NY-REN-64

Locus: 12q12

Protein: Interleukin-1 receptor associated kinase 4 mutant form 1

 

Disorders

Tests

Test Type
Molecular (15)
Multi-Gene Panel (3)
Multi-Method Panel (3)
Test Method
Del/Dup (CNV) (5)
Sequencing, Capillary (Sanger) (9)
Sequencing, Next Gen (4)
Prenatal/Carrier
Prenatal (5)
Carrier (9)
Lab Location
Portugal(4)
USA(7)
Germany(3)
Canada(1)
 
TAT: 11-12 weeks
price: contact lab
IRAK4 Gene Sequencing
method(s): ◦ Sequencing, Capillary (Sanger) 
Cincinnati Children's Hospital Medical Center, Molecular Genetics Laboratory - Cincinnati, OH, USA
TAT: 3-4 weeks
price: contact lab
IRAK4 Del/Dup
method(s): ◦ Del/Dup (CNV) 
GeneDx - Gaithersburg, MD, USA
TAT: 5-6 weeks
price: contact lab
IRAK4 Gene Sequencing
method(s): ◦ Sequencing, Capillary (Sanger) 
GeneDx - Gaithersburg, MD, USA
TAT: 4 weeks
price: contact lab
IRAK4 Deletion/duplication analysis
method(s): ◦ Del/Dup (CNV) 
Cincinnati Children's Hospital Medical Center, Molecular Genetics Laboratory - Cincinnati, OH, USA
IRAK4 deficiency (sequence analysis or IRAK4 gene)
method(s): ◦ Sequencing, Capillary (Sanger) 
CGC Genetics - Porto, Portugal
Increased risk for infection with Gram-positive bacteria (c.1282G>A SNP on IRAK4 gene)
method(s): ◦ Sequencing, Capillary (Sanger) 
CGC Genetics - Porto, Portugal
Primary immunodeficiency due to IRAK4 deficiency (sequence analysis of IRAK4 gene)
method(s): ◦ Sequencing, Capillary (Sanger) 
CGC Genetics - Porto, Portugal
TAT: 4-6 weeks
price: contact lab
Defects in Innate Immunity Panel
method(s): ◦ Sequencing, Next Gen 
CeGaT GmbH - Tübingen, Germany
TAT: 4-5 Weeks
price: contact lab
IRAK4
method(s): ◦ Sequencing, Next Gen ◦ Sequencing, Capillary (Sanger) ◦ Del/Dup (CNV) 
Fulgent Diagnostics - Temple City, CA, USA
Defects in intrinsic and innate immunity - predominant susceptibility to invasive infections with pyogenic bacteria (NGS panel of 2 genes)
method(s): ◦ Sequencing, Next Gen 
CGC Genetics - Porto, Portugal
TAT: 3-4 weeks
price: $690.00
Primary Immunodeficiency via the IRAK4 Gene
method(s): ◦ Del/Dup (CNV) 
PreventionGenetics (Prevention Genetics), Clinical DNA Testing and DNA Banking - Marshfield, WI, USA
TAT: 2-3 weeks
price: $910.00
Primary Immunodeficiency via the IRAK4 Gene
method(s): ◦ Sequencing, Capillary (Sanger) 
PreventionGenetics (Prevention Genetics), Clinical DNA Testing and DNA Banking - Marshfield, WI, USA
TAT: ~2 weeks
price: contact lab
IRAK4 deficiency
method(s): ◦ Sequencing, Capillary (Sanger) 
Centogene AG, Rare Disease Company - Rostock, Germany
CEN4GEN Breast cancer: Extended Sequencing Panel
method(s): ◦ Sequencing, Next Gen 
CEN4GEN Institute for Genomics and Molecular Diagnostics - Edmonton, Canada
TAT: ~2 weeks
price: contact lab
Invasive pneumococcal disease, recurrent isolated type 1
method(s): ◦ Sequencing, Capillary (Sanger) ◦ Del/Dup (CNV) 
Centogene AG, Rare Disease Company - Rostock, Germany