SMAD4

OMIMHGNC

Synonym(s): DPC4, MADH4

Locus: 18q21.1

Protein: Mothers against decapentaplegic homolog 4

 

Disorders

Filter By:

Test Type
Molecular
Cytogenetic
Panel
Test Method
Sequencing, Capillary (Sanger)
Sequencing, Next Gen
Deletion / Duplication / Copy Number (Array, MLPA, Q-PCR, etc.)
Mutation Scanning of Entire Coding Region
Prenatal/Carrier
Prenatal
Carrier
Lab Location
Australia
Canada
Denmark
Estonia
Germany
Spain
USA

Tests

Test
TAT: 6-7 weeks
price: contact lab
BMPR1A, SMAD4 Gene Sequencing and Del/Dup
method(s): ◦ Sequencing, Capillary (Sanger) ◦ Deletion / Duplication / Copy Number (Array, MLPA, Q-PCR, etc.) 
GeneDx - Gaithersburg, MD, USA
TAT: 4-6 weeks
price: contact lab
Breast Ovarian Cancer NGS Panel
method(s): ◦ Sequencing, Next Gen 
Fulgent Diagnostics - Temple City, CA, USA
TAT: 3-5 weeks
price: $3,790.00
Cancer Deletion/Duplication Panel
method(s): ◦ Deletion / Duplication / Copy Number (Array, MLPA, Q-PCR, etc.) 
PreventionGenetics (Prevention Genetics), Clinical DNA Testing and DNA Banking - Marshfield, WI, USA
TAT: 5-7 weeks
price: $3,890.00
Cancer NextGen Sequencing (NGS) Panel
method(s): ◦ Sequencing, Next Gen 
PreventionGenetics (Prevention Genetics), Clinical DNA Testing and DNA Banking - Marshfield, WI, USA
TAT: 8-10 weeks
price: contact lab
Cancer: Familial/Multiple Cancer (Not Specified) Multi-Gene Panel
method(s): ◦ Sequencing, Next Gen 
MGZ München, Medizinisch Genetisches Zentrum München - München, Germany
TAT: 8-10 weeks
price: contact lab
Cancer: Hereditary Colorectal Cancer Multi-Gene Panel
method(s): ◦ Sequencing, Next Gen 
MGZ München, Medizinisch Genetisches Zentrum München - München, Germany
TAT: 4-6 weeks
price: contact lab
Colon Rectal Cancer NGS Panel
method(s): ◦ Sequencing, Next Gen 
Fulgent Diagnostics - Temple City, CA, USA
TAT: 10 weeks
price: contact lab
Colorectal Cancer Panel
method(s): ◦ Sequencing, Next Gen ◦ Deletion / Duplication / Copy Number (Array, MLPA, Q-PCR, etc.) 
GeneDx - Gaithersburg, MD, USA
TAT: 10 weeks
price: contact lab
Comprehensive Cancer Panel
method(s): ◦ Sequencing, Next Gen ◦ Deletion / Duplication / Copy Number (Array, MLPA, Q-PCR, etc.) 
GeneDx - Gaithersburg, MD, USA
TAT: 3-5 weeks
price: $2,690.00
Gastrointestinal Cancer Deletion/Duplication Panel
method(s): ◦ Deletion / Duplication / Copy Number (Array, MLPA, Q-PCR, etc.) 
PreventionGenetics (Prevention Genetics), Clinical DNA Testing and DNA Banking - Marshfield, WI, USA
TAT: 5-7 weeks
price: $3,590.00
Gastrointestinal Cancer NextGen Sequencing (NGS) Panel
method(s): ◦ Sequencing, Next Gen 
PreventionGenetics (Prevention Genetics), Clinical DNA Testing and DNA Banking - Marshfield, WI, USA
TAT: 4-6 weeks
price: contact lab
Hereditary Cancer Panel
method(s): ◦ Sequencing, Next Gen 
Fulgent Diagnostics - Temple City, CA, USA
TAT: 12-13 weeks
price: contact lab
Hereditary Cancer Syndrome: Sequencing Panel
method(s):
Emory University School of Medicine, Emory Molecular Genetics Laboratory - Atlanta, GA, USA
Hereditary Colon Cancer Del/Dup
method(s): ◦ Deletion / Duplication / Copy Number (Array, MLPA, Q-PCR, etc.) 
Mayo Clinic - Minnesota, Molecular Genetics Laboratory - Rochester, MN, USA
Hereditary Colon Cancer Panel
method(s): ◦ Sequencing, Next Gen ◦ Sequencing, Capillary (Sanger) ◦ Deletion / Duplication / Copy Number (Array, MLPA, Q-PCR, etc.) 
Mayo Clinic - Minnesota, Molecular Genetics Laboratory - Rochester, MN, USA
TAT: 2-3 weeks
price: contact lab
Hereditary Colorectal Cancer DNA Insight
method(s): ◦ Sequencing, Next Gen ◦ Sequencing, Capillary (Sanger) 
Pathway Genomics Corporation - San Diego, USA
TAT: 10 weeks
price: contact lab
Hereditary colorectal cancer panel
method(s): ◦ Sequencing, Next Gen ◦ Deletion / Duplication / Copy Number (Array, MLPA, Q-PCR, etc.) 
Aarhus University Hospital, Department of Molecular Medicine - Aarhus, Denmark
TAT: 4-6 weeks
price: contact lab
Hereditary Hemorrhagic Telangiectasia
method(s): ◦ Sequencing, Capillary (Sanger) ◦ Deletion / Duplication / Copy Number (Array, MLPA, Q-PCR, etc.) 
Hospital for Sick Children, Molecular Genetics Laboratory - Toronto, Canada
TAT: 3-5 weeks
price: $1,290.00
Hereditary Hemorrhagic Telangiectasia (HHT) Deletion/Duplication Panel
method(s): ◦ Deletion / Duplication / Copy Number (Array, MLPA, Q-PCR, etc.) 
PreventionGenetics (Prevention Genetics), Clinical DNA Testing and DNA Banking - Marshfield, WI, USA
TAT: 4-6 weeks
price: $2,150.00
Hereditary Hemorrhagic Telangiectasia (HHT) Sanger Sequencing Panel
method(s): ◦ Sequencing, Capillary (Sanger) 
PreventionGenetics (Prevention Genetics), Clinical DNA Testing and DNA Banking - Marshfield, WI, USA
TAT: 4-6 weeks
price: contact lab
Hereditary Hemorrhagic Telangiectasia (HTT) NGS Panel
method(s): ◦ Sequencing, Next Gen 
Fulgent Diagnostics - Temple City, CA, USA
TAT: 10-12 weeks
price: contact lab
Hereditary Hemorrhagic Telangiectasia Panel
method(s): ◦ Sequencing, Next Gen ◦ Deletion / Duplication / Copy Number (Array, MLPA, Q-PCR, etc.) 
GeneDx - Gaithersburg, MD, USA
TAT: 2-4 weeks
price: contact lab
Hereditary Hemorrhagic telangiectasia type 1 (HHT1) / 2 (HHT2) / 5 (HHT5) / SMAD4 related
method(s): ◦ Sequencing, Capillary (Sanger) ◦ Deletion / Duplication / Copy Number (Array, MLPA, Q-PCR, etc.) 
Connective Tissue Gene Tests - Allentown, PA, USA
TAT: 2-4 weeks
price: contact lab
Hereditary Hemorrhagic telangiectasia type 1 (HHT1) / 2 (HHT2) / 5 (HHT5) / SMAD4 related
method(s): ◦ Deletion / Duplication / Copy Number (Array, MLPA, Q-PCR, etc.) 
Connective Tissue Gene Tests - Allentown, PA, USA
TAT: 2 weeks
price: contact lab
Hereditary Hemorrhagic telangiectasia type 1 (HHT1) / 2 (HHT2) / 5 (HHT5) / SMAD4 related
method(s): ◦ Sequencing, Capillary (Sanger) 
Connective Tissue Gene Tests - Allentown, PA, USA
TAT: contact lab
price: $3,000.00
iGene Cancer (Risk Prediction)
method(s): ◦ Sequencing, Next Gen 
ApolloGen, Inc. - Irvine, CA, USA
TAT: 10 weeks
price: $5,500.00
iGene Comprehensive (Cancer, Cardiac, Drug Sensitivity)
method(s): ◦ Sequencing, Next Gen 
ApolloGen, Inc. - Irvine, CA, USA
TAT: 3-4 weeks
price: contact lab
JPS Del/Dup Analysis
method(s): ◦ Deletion / Duplication / Copy Number (Array, MLPA, Q-PCR, etc.) 
GeneDx - Gaithersburg, MD, USA
TAT: 6-7 weeks
price: contact lab
JPS Tier 1
method(s): ◦ Sequencing, Capillary (Sanger) ◦ Deletion / Duplication / Copy Number (Array, MLPA, Q-PCR, etc.) 
GeneDx - Gaithersburg, MD, USA
TAT: 3-4 weeks
price: $770.00
Juvenile Polyposis Syndrome (JPS) and Hereditary Hemorrhagic Telangiectasia (HHT) via the SMAD4 Gene
method(s): ◦ Sequencing, Capillary (Sanger) 
PreventionGenetics (Prevention Genetics), Clinical DNA Testing and DNA Banking - Marshfield, WI, USA
TAT: 3-5 weeks
price: $990.00
Juvenile Polyposis Syndrome (JPS) and Hereditary Hemorrhagic Telangiectasia (HHT) via the SMAD4 Gene
method(s): ◦ Deletion / Duplication / Copy Number (Array, MLPA, Q-PCR, etc.) 
PreventionGenetics (Prevention Genetics), Clinical DNA Testing and DNA Banking - Marshfield, WI, USA
TAT: 4-5 weeks
price: contact lab
Juvenile Polyposis Syndrome: SMAD4 Gene Deletion/Duplication
method(s):
Emory University School of Medicine, Emory Molecular Genetics Laboratory - Atlanta, GA, USA
TAT: 4-5 weeks
price: contact lab
Juvenile Polyposis Syndrome: SMAD4 Gene Sequencing
method(s):
Emory University School of Medicine, Emory Molecular Genetics Laboratory - Atlanta, GA, USA
Juvenile Polyposis, Sequencing SMAD4 (MADH4) Gene
method(s): ◦ Sequencing, Capillary (Sanger) 
Reference Laboratory Genetics - Barcelona, Spain
TAT: 2-4 weeks
price: contact lab
Juvenile polyposis/hereditary hemorrhagic telangiectasia syndrome (JPHT)
method(s): ◦ Sequencing, Capillary (Sanger) ◦ Deletion / Duplication / Copy Number (Array, MLPA, Q-PCR, etc.) 
Connective Tissue Gene Tests - Allentown, PA, USA
TAT: 2-4 weeks
price: contact lab
Juvenile polyposis/hereditary hemorrhagic telangiectasia syndrome (JPHT)
method(s): ◦ Deletion / Duplication / Copy Number (Array, MLPA, Q-PCR, etc.) 
Connective Tissue Gene Tests - Allentown, PA, USA
TAT: 2 weeks
price: contact lab
Juvenile polyposis/hereditary hemorrhagic telangiectasia syndrome (JPHT)
method(s): ◦ Sequencing, Capillary (Sanger) 
Connective Tissue Gene Tests - Allentown, PA, USA
TAT: 8-10 weeks
price: contact lab
Juvenile Polyposis/Hereditary Hemorrhagic Telangiectasia Syndrome Test
method(s): ◦ Sequencing, Capillary (Sanger) 
University of Pennsylvania School of Medicine, Genetic Diagnostic Laboratory - Philadelphia, PA, USA
TAT: 13-15 weeks
price: contact lab
Lynch Syndrome and Polyposis Syndrome
method(s): ◦ Sequencing, Next Gen 
Asper Biotech Ltd., Asper Biotech - Tartu, Estonia
TAT: 6-7 weeks
price: contact lab
MLPA detection of large deletions and duplications in the SMAD4 and BMPR1A genes
method(s): ◦ Deletion / Duplication / Copy Number (Array, MLPA, Q-PCR, etc.) 
Sistemas Genomicos, Medical Genetics Unit - Paterna, Spain
TAT: 2-4 weeks
price: contact lab
Myhre syndrome (MYHRS)
method(s): ◦ Sequencing, Capillary (Sanger) 
Connective Tissue Gene Tests - Allentown, PA, USA
myRisk® Test
method(s): ◦ Sequencing, Next Gen 
Genetic Technologies Pty Ltd - Victoria, Australia
TAT: 7-8 weeks
price: contact lab
NGS and detection of deletions/duplications by MLPA of 3 genes: BMPR1A, PTEN, SMAD4
method(s): ◦ Sequencing, Next Gen ◦ Mutation Scanning of Entire Coding Region ◦ Deletion / Duplication / Copy Number (Array, MLPA, Q-PCR, etc.) 
Sistemas Genomicos, Medical Genetics Unit - Paterna, Spain
TAT: 7-8 weeks
price: contact lab
NGS of 3 genes: SMAD4, PTEN, STK11.
method(s): ◦ Sequencing, Next Gen ◦ Mutation Scanning of Entire Coding Region 
Sistemas Genomicos, Medical Genetics Unit - Paterna, Spain
TAT: 10 weeks
price: contact lab
Polyposis panel
method(s): ◦ Sequencing, Next Gen ◦ Deletion / Duplication / Copy Number (Array, MLPA, Q-PCR, etc.) 
Aarhus University Hospital, Department of Molecular Medicine - Aarhus, Denmark
TAT: 6-7 weeks
price: contact lab
Sanger sequencing of the SMAD4 gene
method(s): ◦ Mutation Scanning of Entire Coding Region ◦ Sequencing, Capillary (Sanger) 
Sistemas Genomicos, Medical Genetics Unit - Paterna, Spain
Single-gene Large Del/Dup
method(s): ◦ Deletion / Duplication / Copy Number (Array, MLPA, Q-PCR, etc.) 
Mayo Clinic - Minnesota, Molecular Genetics Laboratory - Rochester, MN, USA
TAT: 3-5 weeks
price: contact lab
SMAD4 Gene Sequencing and Del/Dup
method(s): ◦ Sequencing, Capillary (Sanger) ◦ Deletion / Duplication / Copy Number (Array, MLPA, Q-PCR, etc.) 
Center for Human Genetics and Laboratory Medicine Martinsried, Molecular Genetics - Martinsried, Germany
SMAD4 Gene, Full Gene Analysis
method(s): ◦ Deletion / Duplication / Copy Number (Array, MLPA, Q-PCR, etc.) ◦ Sequencing, Capillary (Sanger) 
Mayo Clinic - Minnesota, Molecular Genetics Laboratory - Rochester, MN, USA
SMAD4 Gene, Known Mutation
method(s): ◦ Sequencing, Capillary (Sanger) 
Mayo Clinic - Minnesota, Molecular Genetics Laboratory - Rochester, MN, USA
TAT: 8-10 weeks
price: contact lab
SMAD4-Related Hereditary Hemorrhagic Telangiectasia Test
method(s): ◦ Sequencing, Capillary (Sanger) 
University of Pennsylvania School of Medicine, Genetic Diagnostic Laboratory - Philadelphia, PA, USA
TAT: 8-10 weeks
price: contact lab
SMAD4-Related Juvenile Polyposis Test
method(s): ◦ Sequencing, Capillary (Sanger) 
University of Pennsylvania School of Medicine, Genetic Diagnostic Laboratory - Philadelphia, PA, USA
TAT: 5-6 weeks
price: contact lab
Targeted Tumor Mutation: Sequencing Panel
method(s):
Emory University School of Medicine, Emory Molecular Genetics Laboratory - Atlanta, GA, USA