Disorders

Spastic Paraplegia 4

Synonym(s): Hereditary Spastic Paraplegia, Spastin Type, HSP4, SPAST-Associated HSP, Spastic Paraplegia Type 4, SPG 4, SPG4

GeneReview OMIM

Gene	Locus	Protein
SPAST	2p24-p21	Spastin

Laboratory	Test Method	Prenatal	Carrier *
Athena Diagnostics Inc, Reference Lab - Worcester, MA, USA
Burc Molecular Genetics Laboratory - Istanbul, Turkey
CeGaT GmbH - Tuebingen, Germany
Center for Human Genetics - University of Regensburg, Hehr Laboratory - Regensburg, Germany
Centogene AG, Rare Disease Company - Rostock, Germany
Diagenom GmbH, Medical Genetics Laboratory - Rostock, Germany
diagenos - Osnabrueck, Germany
Edith Wolfson Medical Center, Molecular Genetics Laboratory - Holon, Israel
GENETAQ, Molecular Genetics Centre - Malaga, Spain
GGA - Galil Genetic Analysis - Kazerin, Israel
GSTS Pathology, DNA Laboratory - London, Great Britain
Instituto de Medicina Genmica, IMEGEN - Paterna, Spain
InVitae Corporation - San Francisco, CA, USA
Laboratory for Molecular Diagnostics, Labor-MVZ Westmecklenburg - Schwerin, Germany
Medgene, MedGene - Bratislava, Slovakia
Medical Neurogenetics - Atlanta, GA, USA
Praxis fuer Humangenetik Wien - Vienna, Austria
Radboud University Nijmegen Medical Centre, Genome Diagnostics Nijmegen - Nijmegen, Netherlands
Ruhr University, Human Genetics - Bochum, Germany
Samsung Medical Center, Department of Laboratory Medicine and Genetics - Seoul, South Korea
Seoul National University Hospital, Molecular Diagnostics Laboratory - Seoul, South Korea
Sheffield Children's NHS Foundation Trust, Sheffield Diagnostic Genetics Service - Sheffield, Great Britain
University Hospital of Tuebingen, Medical Genetics Tuebingen - Tuebingen, Germany
University of Goettingen, Institute of Human Genetics - Goettingen, Germany
University of Turku, Diagnostic DNA Laboratory - Turku, Finland

^* Carrier column is relevant to autosomal recessive and X-linked inheritance; column will be blank when it is not relevant (e.g. autosomal dominant inheritance, microdeletions/duplications) and/or is not offered by the lab.