Disorders

OTOF-Related Deafness

Synonym(s): DFNB 9, DFNB 9 Nonsyndromic Hearing Loss and Deafness, DFNB9

Gene	Locus	Protein
OTOF	2p23.1

Laboratory	Test Method	Prenatal	Carrier *
CeGaT GmbH - Tuebingen, Germany
Center for Human Genetics, Bioscientia GmbH - Ingelheim, Germany
Centogene AG, Rare Disease Company - Rostock, Germany
CGC Genetics - Porto, Portugal	• Sequence analysis of select exons
Cincinnati Children's Hospital Medical Center, Molecular Genetics Laboratory - Cincinnati, OH, USA
Cliniques universitaires Saint Luc, Center for Human Genetics - Brussels, Belgium
GENETAQ, Molecular Genetics Centre - Malaga, Spain
Harvard Medical School and Partners Healthcare, Laboratory for Molecular Medicine - Cambridge, MA, USA
Instituto de Medicina Genmica, IMEGEN - Paterna, Spain	• Targeted mutation analysis
Radboud University Nijmegen Medical Centre, Genome Diagnostics Nijmegen - Nijmegen, Netherlands
Sistemas Genomicos, Medical Genetics Unit - Paterna, Spain	• Sequence analysis of select exons

^* Carrier column is relevant to autosomal recessive and X-linked inheritance; column will be blank when it is not relevant (e.g. autosomal dominant inheritance, microdeletions/duplications) and/or is not offered by the lab.