Disorders

Alzheimer Disease Type 4

Synonym(s): AD 4, AD4

Gene	Locus	Protein
PSEN2	1q31-q42	Presenilin-2

Laboratory	Test Method	Prenatal	Carrier *
Athena Diagnostics Inc, Reference Lab - Worcester, MA, USA
CeGaT GmbH - Tuebingen, Germany
Centogene AG, Rare Disease Company - Rostock, Germany
Diagenom GmbH, Medical Genetics Laboratory - Rostock, Germany
Dr. Eberhard and Partner, MVZ Dortmund - Dortmund, Germany
Edith Wolfson Medical Center, Molecular Genetics Laboratory - Holon, Israel
GENETAQ, Molecular Genetics Centre - Malaga, Spain	• Mutation scanning of select exons
Instituto de Medicina Genmica, IMEGEN - Paterna, Spain
Laboratory for Molecular Diagnostics, Labor-MVZ Westmecklenburg - Schwerin, Germany
MGZ München, Medizinisch Genetisches Zentrum München - München, Germany
Secugen SL - Madrid, Spain
Sistemas Genomicos, Medical Genetics Unit - Paterna, Spain
University Hospital Ostrava, DNA Diagnostics Laboratory - Ostrava, Czech Republic

^* Carrier column is relevant to autosomal recessive and X-linked inheritance; column will be blank when it is not relevant (e.g. autosomal dominant inheritance, microdeletions/duplications) and/or is not offered by the lab.