Disorders

Multicentric Carpotarsal Osteolysis Syndrome

Synonym(s): Hereditary Osteolysis of Carpal Bones with or without Nephropathy, MCTO, Multicentric Osteolysis of Carpal Bones and Nephropathy, Multicentric Osteolysis, Autosomal Dominant

OMIM

Gene	Locus	Protein
MAFB	20q11.1-q13.1	Transcription factor MafB

Laboratory	Test Method	Prenatal	Carrier *
Centogene AG, Rare Disease Company - Rostock, Germany	• Sequence analysis of the entire coding region • Deletion/duplication analysis

^* Carrier column is relevant to autosomal recessive and X-linked inheritance; column will be blank when it is not relevant (e.g. autosomal dominant inheritance, microdeletions/duplications) and/or is not offered by the lab.