Disorders

SMAD3-Related Thoracic Aortic Aneurysms and Aortic Dissections

Synonym(s): SMAD3-Related TAAD

Gene	Locus	Protein
SMAD3	15q21-q22	Mothers against decapentaplegic homolog 3

Laboratory	Test Method	Prenatal	Carrier *
BC Children's and BC Women's Hospitals, Molecular Genetics Laboratory - Vancouver, Canada
Center for Human Genetics, Inc - Cambridge, MA, USA
Connective Tissue Gene Tests - Allentown, PA, USA
Johns Hopkins Hospital, DNA Diagnostic Laboratory - Baltimore, MD, USA
Klinikum Stuttgart, Institute of Clinical Genetics - Stuttgart, Germany
PreventionGenetics, Clinical DNA Testing and DNA Banking - Marshfield, WI, USA
University of Washington Medical Center, Collagen Diagnostic Laboratory - Seattle, WA, USA

^* Carrier column is relevant to autosomal recessive and X-linked inheritance; column will be blank when it is not relevant (e.g. autosomal dominant inheritance, microdeletions/duplications) and/or is not offered by the lab.