Disorders

MAP2K1-Related Noonan Syndrome

Gene	Locus	Protein
MAP2K1	15q22.1-q22.33	Dual specificity mitogen-activated protein kinase kinase 1

Laboratory	Test Method	Prenatal	Carrier *
Baylor College of Medicine, Medical Genetics Laboratories - Houston, TX, USA
Children's Hospital of Philadelphia, Molecular Genetics Laboratory - Philadelphia, PA, USA
diagenos - Osnabrueck, Germany
Greenwood Genetic Center, Molecular Diagnostic Laboratory - Greenwood, SC, USA
Harvard Medical School and Partners Healthcare, Laboratory for Molecular Medicine - Cambridge, MA, USA
Radboud University Nijmegen Medical Centre, Genome Diagnostics Nijmegen - Nijmegen, Netherlands
University of Oklahoma Health Sciences Center, Genetics Laboratory - Oklahoma City, OK, USA

^* Carrier column is relevant to autosomal recessive and X-linked inheritance; column will be blank when it is not relevant (e.g. autosomal dominant inheritance, microdeletions/duplications) and/or is not offered by the lab.