Disorders

Primary Hypertrophic Osteoarthropathy, Autosomal Recessive

Synonym(s): Pachydermoperiostosis, Autosomal Recessive, Touraine-Solente-Gole Syndrome

Gene	Locus	Protein
HPGD	4q34-q35	15-hydroxyprostaglandin dehydrogenase [NAD(+)]

Laboratory	Test Method	Prenatal	Carrier *
Center for Human Genetics, Bioscientia GmbH - Ingelheim, Germany	• Linkage analysis
St James's University Hospital, Leeds Teaching Hospitals, Yorkshire Regional DNA Laboratory - Leeds, Great Britain

^* Carrier column is relevant to autosomal recessive and X-linked inheritance; column will be blank when it is not relevant (e.g. autosomal dominant inheritance, microdeletions/duplications) and/or is not offered by the lab.