Disorders

DFNA20/26 Nonsyndromic Hearing Loss and Deafness

Synonym(s): DFNA 20, DFNA 20/26, DFNA 26, DFNA20, DFNA20/26, DFNA26

Gene	Locus	Protein
ACTG1	17q25	Actin, cytoplasmic 2

Laboratory	Test Method	Prenatal	Carrier *
Center for Human Genetics, Bioscientia GmbH - Ingelheim, Germany	• Sequence analysis of the entire coding region
Centogene AG, Rare Disease Company - Rostock, Germany	• Sequence analysis of the entire coding region • Deletion/duplication analysis
Radboud University Nijmegen Medical Centre, Genome Diagnostics Nijmegen - Nijmegen, Netherlands	• Sequence analysis of the entire coding region

^* Carrier column is relevant to autosomal recessive and X-linked inheritance; column will be blank when it is not relevant (e.g. autosomal dominant inheritance, microdeletions/duplications) and/or is not offered by the lab.