Disorders

YARS-Related Intermediate Charcot-Marie-Tooth Neuropathy

Synonym(s): Charcot-Marie-Tooth Neuropathy, Dominant Intermediate C, CMTDIC, DI-CMTC

Gene	Locus	Protein
YARS	1p35.1	Tyrosyl-tRNA synthetase, cytoplasmic

Laboratory	Test Method	Prenatal	Carrier *
Centogene AG, Rare Disease Company - Rostock, Germany
Diagenom GmbH, Medical Genetics Laboratory - Rostock, Germany	• Sequence analysis of select exons
InVitae Corporation - San Francisco, CA, USA
MGZ München, Medizinisch Genetisches Zentrum München - München, Germany

^* Carrier column is relevant to autosomal recessive and X-linked inheritance; column will be blank when it is not relevant (e.g. autosomal dominant inheritance, microdeletions/duplications) and/or is not offered by the lab.