Disorders

DNM2-Related Intermediate Charcot-Marie-Tooth Neuropathy

Synonym(s): AD Charcot-Marie-Tooth Disease Type 2B, Charcot-Marie-Tooth Disease, Dominant Intermediate B, Charcot-Marie-Tooth Neuropathy, Dominant Intermediate B, CMTDI1, DI-CMTB, DNM2-CMT2B

GeneReview OMIM

Gene	Locus	Protein
DNM2	19p	Dynamin-2

Laboratory	Test Method	Prenatal	Carrier *
Center for Human Genetics, Bioscientia GmbH - Ingelheim, Germany	• Linkage analysis
Centogene AG, Rare Disease Company - Rostock, Germany
Diagenom GmbH, Medical Genetics Laboratory - Rostock, Germany	• Sequence analysis of select exons
HIBM Research Group - Reseda, CA, USA
InVitae Corporation - San Francisco, CA, USA
MGZ München, Medizinisch Genetisches Zentrum München - München, Germany
PreventionGenetics, Clinical DNA Testing and DNA Banking - Marshfield, WI, USA
University of Chicago, Genetic Services Laboratory - Chicago, IL, USA

^* Carrier column is relevant to autosomal recessive and X-linked inheritance; column will be blank when it is not relevant (e.g. autosomal dominant inheritance, microdeletions/duplications) and/or is not offered by the lab.