Disorders

Vitamin K-Dependent Clotting Factors, Combined Deficiency of, 1

Synonym(s): Familial Multiple Coagulation Factor Deficiency III, Vitamin K-Dependent Coagulation Defect, VKCFD1

Gene	Locus	Protein
GGCX	2p12	Vitamin K-dependent gamma-carboxylase

Laboratory	Test Method	Prenatal	Carrier *
Center for Nephrology and Metabolic Disorders, Laboratory for Molecular Diagnostics - Weisswasser, Germany	• Sequence analysis of the entire coding region

^* Carrier column is relevant to autosomal recessive and X-linked inheritance; column will be blank when it is not relevant (e.g. autosomal dominant inheritance, microdeletions/duplications) and/or is not offered by the lab.