Disorders

Multicentric Osteolysis, Nodulosis, and Arthropathy

Synonym(s): Idiopathic Osteolysis, Saudi Type, NAO Syndrome

Gene	Locus	Protein
MMP2	16q13-q21	72 kDa type IV collagenase

Laboratory	Test Method	Prenatal	Carrier *
Centre for Clinical Research - University of Queensland, Bone Dysplasia Research Group - Brisbane, Australia
University of Lausanne, Division of Molecular Pediatrics - Lausanne, Switzerland

^* Carrier column is relevant to autosomal recessive and X-linked inheritance; column will be blank when it is not relevant (e.g. autosomal dominant inheritance, microdeletions/duplications) and/or is not offered by the lab.