Disorders

Mast Syndrome

Synonym(s): HSP21, Spastic Paraplegia 21, SPG 21, SPG21

Gene	Locus	Protein
SPG21	15q21-q22	Maspardin

Laboratory	Test Method	Prenatal	Carrier *
Centogene AG, Rare Disease Company - Rostock, Germany
Diagenom GmbH, Medical Genetics Laboratory - Rostock, Germany
GENETAQ, Molecular Genetics Centre - Malaga, Spain
Hospital for Sick Children, Molecular Genetics Laboratory - Toronto, Canada
InVitae Corporation - San Francisco, CA, USA
Radboud University Nijmegen Medical Centre, Genome Diagnostics Nijmegen - Nijmegen, Netherlands
University Hospitals - University Hospitals Laboratory Service Foundation, Center for Human Genetics Laboratory - Cleveland, OH, USA	• Targeted mutation analysis

^* Carrier column is relevant to autosomal recessive and X-linked inheritance; column will be blank when it is not relevant (e.g. autosomal dominant inheritance, microdeletions/duplications) and/or is not offered by the lab.