Disorders

SCN5A-Related Dilated Cardiomyopathy

Synonym(s): CMD1E, Dilated Cardiomyopathy 1E

Gene	Locus	Protein
SCN5A	3p21	Sodium channel protein type 5 subunit alpha

Laboratory	Test Method	Prenatal	Carrier *
Academic Medical Centre, University of Amsterdam, DNA Diagnostics Laboratory - Amsterdam, Netherlands
Centogene AG, Rare Disease Company - Rostock, Germany
CGC Genetics - Porto, Portugal
Cincinnati Children's Hospital Medical Center, Heart Institute Diagnostic Lab - Cincinnati, OH, USA
Diagenom GmbH, Medical Genetics Laboratory - Rostock, Germany
GeneDx - Gaithersburg, MD, USA
GGA - Galil Genetic Analysis - Kazerin, Israel
Health in Code S.L. - A Coruña, Spain
IRCCS Fondazione Salvatore Maugeri, Molecular Cardiology Laboratories - Pavia, Italy
Laboratory for Molecular Diagnostics, Labor-MVZ Westmecklenburg - Schwerin, Germany
LabPLUS - Auckland City Hospital, Molecular Genetics Laboratory - Diagnostics Genetics - Auckland, New Zealand
Maastricht University Medical Centre, Clinical Genomics - Maastricht, Netherlands
Oslo University Hospital HF - Ullevaal, Department of Medical Genetics - Unit for Cardiac and Cardiavasular Genetics - Oslo, Norway
Sistemas Genomicos, Medical Genetics Unit - Paterna, Spain
Transgenomic - New Haven, CT, USA
University Hospital Münster, Institute for Genetics of Heart Diseases (IfGH) - Münster, Germany

^* Carrier column is relevant to autosomal recessive and X-linked inheritance; column will be blank when it is not relevant (e.g. autosomal dominant inheritance, microdeletions/duplications) and/or is not offered by the lab.