Disorders

LAMA2-Related Muscular Dystrophy

Synonym(s): Early-Onset Laminin Alpha 2 Deficiency, Laminin Alpha 2-Deficient Congenital Muscular Dystrophy , Late-Onset Laminin Alpha 2 Deficiency, MDC 1A, MDC IA, MDC1A, MDCIA, Merosin-Deficient Congenital Muscular Dystrophy Type 1A

GeneReview OMIM

Gene	Locus	Protein
LAMA2	6q22-q23	Laminin subunit alpha-2

Laboratory	Test Method	Prenatal	Carrier *
Athena Diagnostics Inc, Reference Lab - Worcester, MA, USA
Centogene AG, Rare Disease Company - Rostock, Germany
CGC Genetics - Porto, Portugal
Emory University School of Medicine, Emory Molecular Genetics Laboratory - Atlanta, GA, USA
GENETAQ, Molecular Genetics Centre - Malaga, Spain
GSTS Pathology, DNA Laboratory - London, Great Britain	• Linkage analysis
Medical Neurogenetics - Atlanta, GA, USA
MGZ München, Medizinisch Genetisches Zentrum München - München, Germany
PreventionGenetics, Clinical DNA Testing and DNA Banking - Marshfield, WI, USA
Radboud University Nijmegen Medical Centre, Genome Diagnostics Nijmegen - Nijmegen, Netherlands
Ruhr University, Human Genetics - Bochum, Germany
Sir Ganga Ram Hospital, Center of Medical Genetics - New Delhi, India	• Linkage analysis • Immunohistochemistry
Sistemas Genomicos, Medical Genetics Unit - Paterna, Spain

^* Carrier column is relevant to autosomal recessive and X-linked inheritance; column will be blank when it is not relevant (e.g. autosomal dominant inheritance, microdeletions/duplications) and/or is not offered by the lab.