Disorders

Prader-Willi-Like Syndrome Associated with Chromosome 6

Gene	Locus	Protein
SIM1	6q16.3-q21	Single-minded homolog 1

Laboratory	Test Method	Prenatal	Carrier *
PerkinElmer, Signature Genomic Laboratories - Spokane, WA, USA	• FISH-metaphase

^* Carrier column is relevant to autosomal recessive and X-linked inheritance; column will be blank when it is not relevant (e.g. autosomal dominant inheritance, microdeletions/duplications) and/or is not offered by the lab.