Disorders

Androgen Insensitivity Syndrome

Synonym(s): AIS, Androgen Receptor Deficiency, Androgen Resistance Syndrome, Reifenstein Syndrome, Testicular Feminization

GeneReview OMIM

Gene	Locus	Protein
AR	Xq12	Androgen receptor

Laboratory	Test Method	Prenatal	Carrier *
Addenbrooke's Hospital, Molecular Genetics Laboratory - Cambridge, Great Britain
All Children's Hospital, Clinical Molecular Genetics Laboratory - St. Petersburg, FL, USA
Baylor College of Medicine, Medical Genetics Laboratories - Houston, TX, USA
BC Children's and BC Women's Hospitals, Molecular Genetics Laboratory - Vancouver, Canada
CeGaT GmbH - Tuebingen, Germany
Center for Genetics at Saint Francis, Genetics Laboratory - Tulsa, OK, USA
Center for Human Genetics - University of Regensburg, Hehr Laboratory - Regensburg, Germany
Denver Genetic Laboratories, University of Colorado, DNA Diagnostic Laboratory - Aurora, CO, USA
Edith Wolfson Medical Center, Molecular Genetics Laboratory - Holon, Israel
Endokrinologikum Hamburg - Center for Hormonal and Metabolic Diseases, Prenatal, and Reproductive Medicine, Molecular Diagnostics - Hamburg, Germany
GeneDx - Gaithersburg, MD, USA
GENETAQ, Molecular Genetics Centre - Malaga, Spain
GGA - Galil Genetic Analysis - Kazerin, Israel
Health Care Center GENOMED, Laboratory of Human Genetics - Warsaw, Poland
Instituto de Medicina Genmica, IMEGEN - Paterna, Spain
Karolinska University Hospital, Department of Clinical Genetics - Stockholm, Sweden
Laboratory for Molecular Diagnostics, Labor-MVZ Westmecklenburg - Schwerin, Germany
National Health Laboratory Services, Inherited Metabolic Diseases - Cape Town, South Africa
National University Hospital, Molecular Diagnosis Centre - Department of Laboratory Medicine - Singapore, Singapore	• Sequence analysis of select exons
PerkinElmer, Signature Genomic Laboratories - Spokane, WA, USA	• FISH-metaphase
PreventionGenetics, Clinical DNA Testing and DNA Banking - Marshfield, WI, USA
Seoul National University Hospital, Molecular Diagnostics Laboratory - Seoul, South Korea
Sheffield Children's NHS Foundation Trust, Sheffield Diagnostic Genetics Service - Sheffield, Great Britain
Sir Ganga Ram Hospital, Center of Medical Genetics - New Delhi, India

^* Carrier column is relevant to autosomal recessive and X-linked inheritance; column will be blank when it is not relevant (e.g. autosomal dominant inheritance, microdeletions/duplications) and/or is not offered by the lab.