Disorders

Neurofibromatosis 2

Synonym(s): Acoustic Schwannomas, Bilateral, BANF, Bilateral Acoustic Neurofibromatosis, Central Neurofibromatosis, Neurofibromatosis Type II, NF 2, NF2, Vestibular Schwannoma Neurofibromatosis

GeneReview OMIM

Gene	Locus	Protein
NF2	22q12.2	Merlin

Laboratory	Test Method	Prenatal	Carrier *
Athena Diagnostics Inc, Reference Lab - Worcester, MA, USA	• Mutation scanning of the entire coding region
Boston Children's Hospital, Genetics Diagnostic Laboratory - Waltham, MA, USA
Center for Human Genetics, Inc - Cambridge, MA, USA
Children's University Hospital, Human Genetics - Berne, Switzerland	• Mutation scanning of the entire coding region
Department of Genetics UAB, Medical Genomics Laboratory - Birmingham, AL, USA	• Linkage analysis • FISH-interphase
diagenos - Osnabrueck, Germany
Dr. Eberhard and Partner, MVZ Dortmund - Dortmund, Germany
GENETAQ, Molecular Genetics Centre - Malaga, Spain
GGA - Galil Genetic Analysis - Kazerin, Israel
Innovagenomics S.L, Innovagenomics - Salamanca, Spain	• Mutation scanning of the entire coding region
Institute of Medical and Veterinary Science, Molecular Pathology - Adelaide, Australia
Institute of Predictive and Personalized Medicine of Cancer (IMPPC), Genetic Diagnostics for Hereditary Cancer Unit - Badalona, Spain	• Linkage analysis
Instituto de Medicina Genmica, IMEGEN - Paterna, Spain
Klinikum Stuttgart, Institute of Clinical Genetics - Stuttgart, Germany
Manchester St Mary's Hospital, Regional Genetics Laboratories - Manchester, Great Britain	• Linkage analysis
Massachusetts General Hospital, Neurogenetics DNA Diagnostic Laboratory - Boston, MA, USA	• Mutation scanning of the entire coding region • Linkage analysis
Medgene, MedGene - Bratislava, Slovakia
PerkinElmer, Signature Genomic Laboratories - Spokane, WA, USA	• FISH-metaphase
Praxis fuer Humangenetik Wien - Vienna, Austria
PreventionGenetics, Clinical DNA Testing and DNA Banking - Marshfield, WI, USA
Pronto Diagnostics Ltd., ProntoLab - MLPA Lab - Tel Aviv, Israel
Ruhr University, Human Genetics - Bochum, Germany
Seoul National University Hospital, Molecular Diagnostics Laboratory - Seoul, South Korea
Shaare Zedek Medical Center, Medical Genetics Institute - Jerusalem, Israel	• Linkage analysis
Sistemas Genomicos, Medical Genetics Unit - Paterna, Spain

^* Carrier column is relevant to autosomal recessive and X-linked inheritance; column will be blank when it is not relevant (e.g. autosomal dominant inheritance, microdeletions/duplications) and/or is not offered by the lab.