Disorders

MSX2-Related Craniosynostosis

Synonym(s): Craniosynostosis Type II, Craniosynostosis, Boston Type, Craniosynostosis, Type 2, CRS2

Gene	Locus	Protein
MSX2	5q35.2	Homeobox protein MSX-2

Laboratory	Test Method	Prenatal	Carrier *
Centogene AG, Rare Disease Company - Rostock, Germany
Instituto de Medicina Genmica, IMEGEN - Paterna, Spain
Mount Sinai School of Medicine, Mount Sinai Genetic Testing Laboratory - New York, NY, USA
Oxford Medical Genetics Laboratories, Oxford Genetics Laboratories - Oxford, Great Britain
PerkinElmer, Signature Genomic Laboratories - Spokane, WA, USA	• FISH-metaphase • FISH-interphase
PreventionGenetics, Clinical DNA Testing and DNA Banking - Marshfield, WI, USA

^* Carrier column is relevant to autosomal recessive and X-linked inheritance; column will be blank when it is not relevant (e.g. autosomal dominant inheritance, microdeletions/duplications) and/or is not offered by the lab.