Disorders

Cardiovascular Disease Risk Factor (Apolipoprotein E)

Synonym(s): Cardiovascular Disease Risk Factor (APOE), Coronary Artery Disease Risk Factor (APOE), Coronary Artery Disease Risk Factor (Apolipoprotein E), Hyperlipoproteinemia Type III Risk Factor (APOE)

OMIM

Gene	Locus	Protein
APOE	19q13.31	Apolipoprotein E

Laboratory	Test Method	Prenatal	Carrier *
ARUP Laboratories, Molecular Genetics Laboratory - Salt Lake City, UT, USA	• Targeted mutation analysis
bio.logis Center for Human Genetics - Frankfurt, Germany	• Targeted mutation analysis
Burc Molecular Genetics Laboratory - Istanbul, Turkey	• Targeted mutation analysis
Center for Human Genetics and Laboratory Medicine Martinsried, Molecular Genetics - Martinsried, Germany	• Targeted mutation analysis
Center for Human Genetics, Bioscientia GmbH - Ingelheim, Germany	• Targeted mutation analysis
Center for Nephrology and Metabolic Disorders, Laboratory for Molecular Diagnostics - Weisswasser, Germany	• Targeted mutation analysis
Centogene AG, Rare Disease Company - Rostock, Germany	• Targeted mutation analysis
Centre for Cardiovascular Surgery and Transplantation, Molecular Genetics Laboratory - Brno, Czech Republic	• Targeted mutation analysis
CGB Laboratory Inc - Ostrava, Czech Republic	• Targeted mutation analysis
CGC Genetics - Porto, Portugal	• Targeted mutation analysis
Charles University, 1st Faculty of Medicine, Institute of Clinical Biochemistry and Laboratory Diagnostics - Praha, Czech Republic	• Targeted mutation analysis
Diagenom GmbH, Medical Genetics Laboratory - Rostock, Germany	• Targeted mutation analysis
Diagnostic Services of Manitoba, Health Sciences Centre site, Molecular Diagnostic Laboratory - Winnipeg, Canada	• Targeted mutation analysis
Dr. Eberhard and Partner, MVZ Dortmund - Dortmund, Germany	• Targeted mutation analysis
Duke University Health System, Molecular Diagnostics Laboratory - Durham, NC, USA	• Targeted mutation analysis
GENDA - Ciudad autonoma de Buenos Aires, Argentina	• Targeted mutation analysis
Genetic Diagnosis and Research Center, Genetiks - Istanbul, Turkey	• Targeted mutation analysis
Hospital Sainte-Justine, Molecular Diagnostics Laboratory - Montreal, Canada	• Targeted mutation analysis
Kimball Genetics - A Division of LabCorp, Molecular Diagnostic Laboratory - Denver, CO, USA	• Targeted mutation analysis
Laboratory for Molecular Diagnostics, Labor-MVZ Westmecklenburg - Schwerin, Germany	• Targeted mutation analysis
Mayo Clinic - Minnesota, Molecular Genetics Laboratory - Rochester, MN, USA	• Targeted mutation analysis
McGill University Health Centre, Molecular Diagnostics - Montreal, Canada	• Targeted mutation analysis
Medgene, MedGene - Bratislava, Slovakia	• Targeted mutation analysis
MGZ München, Medizinisch Genetisches Zentrum München - München, Germany	• Targeted mutation analysis
Praxis fuer Humangenetik Wien - Vienna, Austria	• Targeted mutation analysis
Providence Sacred Heart Medical Center and Children's Hospital, Department of Laboratory Medicine/Molecular Diagnostic Division - Spokane, WA, USA	• Targeted mutation analysis
Sheffield Children's NHS Foundation Trust, Sheffield Diagnostic Genetics Service - Sheffield, Great Britain	• Targeted mutation analysis
Sunnybrook Health Sciences Centre, Molecular Genetics Laboratory - Toronto, Canada	• Targeted mutation analysis
Synlab MVZ Humane Genetik Mnchen, Labor fr Humangenetik - München, Germany	• Targeted mutation analysis
University Hospital Ostrava, DNA Diagnostics Laboratory - Ostrava, Czech Republic	• Targeted mutation analysis
University of Kentucky, Immuno-Molecular Pathology - Lexington, KY, USA	• Targeted mutation analysis
University of Michigan, Molecular Diagnostics Laboratory - Ann Arbor, MI, USA	• Targeted mutation analysis

^* Carrier column is relevant to autosomal recessive and X-linked inheritance; column will be blank when it is not relevant (e.g. autosomal dominant inheritance, microdeletions/duplications) and/or is not offered by the lab.