Disorders

HFE-Associated Hereditary Hemochromatosis

Synonym(s): Bronze Diabetes, Hemochromatosis, HFE-Associated Hereditary

Gene	Locus	Protein
HFE	6p21.3	Hereditary hemochromatosis protein

Laboratory	Test Method	Prenatal	Carrier *
Aarhus University Hospital, Aarhus Sygehus - Tage-Hansens Gade, Molecular Genetics Laboratory - Department of Clinical Biochemistry - Aarhus, Denmark	• Targeted mutation analysis
Aarhus University Hospital, Department of Clinical Genetics - Aarhus, Denmark	• Targeted mutation analysis
Alberta Children's Hospital, Molecular Diagnostic Laboratory - Calgary, Canada	• Targeted mutation analysis
All Children's Hospital, Clinical Molecular Genetics Laboratory - St. Petersburg, FL, USA
ARUP Laboratories, Molecular Genetics Laboratory - Salt Lake City, UT, USA	• Targeted mutation analysis
Baylor College of Medicine, Medical Genetics Laboratories - Houston, TX, USA	• Targeted mutation analysis
bio.logis Center for Human Genetics - Frankfurt, Germany	• Targeted mutation analysis
BioAnalytica-GenoType S.A., Molecular Cytogenetic Research and Applications Lab - Athens, Greece	• Targeted mutation analysis
BioLab spol. s.r.o., Molecular Biology Laboratory - Klatovy, Czech Republic	• Targeted mutation analysis
Biyolojik Bilimler Arastirma Gelistirme ve Uretim AS, Duzen Laboratuvarlar Grubu - Istanbul, Turkey	• Targeted mutation analysis
BloodCenter of Wisconsin, Molecular Diagnostics Laboratory - Milwaukee, WI, USA	• Targeted mutation analysis
Burc Molecular Genetics Laboratory - Istanbul, Turkey	• Targeted mutation analysis
CeGaT GmbH - Tuebingen, Germany
Center for Human Genetics and Laboratory Medicine Martinsried, Molecular Genetics - Martinsried, Germany	• Targeted mutation analysis
Center for Human Genetics, Bioscientia GmbH - Ingelheim, Germany	• Targeted mutation analysis
Center for Human Genetics, Inc - Cambridge, MA, USA	• Targeted mutation analysis
Centogene AG, Rare Disease Company - Rostock, Germany
Centre for Cellular and Molecular Biology, Molecular Diagnostics Division - Hyderabad, India	• Targeted mutation analysis
Centre for DNA Fingerprinting and Diagnostics, Diagnostics Division - Hyderabad, India	• Targeted mutation analysis
CGB Laboratory Inc - Ostrava, Czech Republic	• Targeted mutation analysis
CGC Genetics - Porto, Portugal	• Targeted mutation analysis
Children's Hospital of Eastern Ontario, Molecular Genetics Diagnostic Laboratory - Ottawa, Canada	• Targeted mutation analysis
Children's Mercy Hospital and Clinics, Molecular Genetics Laboratory - Kansas City, MO, USA	• Targeted mutation analysis
Children's University Hospital, Human Genetics - Berne, Switzerland	• Mutation scanning of the entire coding region • Targeted mutation analysis
CIBIC S.A. - Rosario, Argentina	• Targeted mutation analysis
Cincinnati Children's Hospital Medical Center, Molecular Genetics Laboratory - Cincinnati, OH, USA	• Targeted mutation analysis
Cyprus Institute of Neurology and Genetics, Molecular Genetics, Function and Therapy - Nicosia, Cyprus	• Targeted mutation analysis
Diagenom GmbH, Medical Genetics Laboratory - Rostock, Germany	• Targeted mutation analysis
diagenos - Osnabrueck, Germany	• Targeted mutation analysis
Diagnostic Services of Manitoba, Health Sciences Centre site, Molecular Diagnostic Laboratory - Winnipeg, Canada	• Targeted mutation analysis
Dr. Eberhard and Partner, MVZ Dortmund - Dortmund, Germany	• Targeted mutation analysis
Duke University Health System, Molecular Diagnostics Laboratory - Durham, NC, USA	• Targeted mutation analysis
Faculty of Medicine, Pontificia Universidad Católica de Chile, Molecular Genetics and Cytogenetics, Clinical Laboratory Service - Santiago, Chile	• Targeted mutation analysis
Furst Medical Laboratories, FurstNAT - Oslo, Norway	• Targeted mutation analysis
GENDA - Ciudad autonoma de Buenos Aires, Argentina	• Targeted mutation analysis
Gene Analysis Service - Berlin, Germany
GENETAQ, Molecular Genetics Centre - Malaga, Spain	• Targeted mutation analysis
Genetic Diagnosis and Research Center, Genetiks - Istanbul, Turkey	• Targeted mutation analysis
Genetrack Biolabs Inc., Molecular Genetics Laboratory - Vancouver, Canada	• Targeted mutation analysis
Genomac International, s.r.o., Laboratory for Molecular Genetics - Prague, Czech Republic	• Targeted mutation analysis
GGA - Galil Genetic Analysis - Kazerin, Israel
Greenwood Genetic Center, Molecular Diagnostic Laboratory - Greenwood, SC, USA	• Targeted mutation analysis
Hamilton Regional Laboratory Medicine Program, Molecular Diagnostic Genetics - Hamilton, Canada	• Targeted mutation analysis
Hartford Hospital-Hartford-CT-USA, Clinical Lab Partners/Molecular Genetics and Cytogenetics - Newington, CT, USA	• Targeted mutation analysis
Health Care Center GENOMED, Laboratory of Human Genetics - Warsaw, Poland	• Targeted mutation analysis
Hopital Saint-Francois d'Assise du CHUQ, Laboratoire de Diagnostic Moleculaire - Quebec City, Canada	• Targeted mutation analysis
HUSLAB, Laboratory of Genetics - Helsinki, Finland	• Targeted mutation analysis
Innovagenomics S.L, Innovagenomics - Salamanca, Spain	• Targeted mutation analysis
Institute of Predictive and Personalized Medicine of Cancer, Advanced Genetic Diagnostic Unit for Rare Iron Metabolism Disorders (UDGAEMH) - Barcelona, Spain
Instituto de Medicina Genmica, IMEGEN - Paterna, Spain	• Targeted mutation analysis
Intergen Genetics Centre - Ankara, Turkey	• Sequence analysis of select exons
InVitae Corporation - San Francisco, CA, USA
Karolinska University Hospital, Department of Clinical Genetics - Stockholm, Sweden	• Targeted mutation analysis
Kimball Genetics - A Division of LabCorp, Molecular Diagnostic Laboratory - Denver, CO, USA	• Targeted mutation analysis
Kingston General Hospital, Molecular Diagnostic Laboratory - Kingston, Canada	• Targeted mutation analysis
Klinikum Stuttgart, Institute of Clinical Genetics - Stuttgart, Germany
LabCorp, Molecular Biology - Research Triangle Park, NC, USA	• Targeted mutation analysis
Laboratory for Molecular Diagnostics, Labor-MVZ Westmecklenburg - Schwerin, Germany
Laboratory for Molecular Genetics, Labor Renner - Kainbach bei Graz, Austria	• Targeted mutation analysis
London Health Sciences Centre, Molecular Diagnostic Laboratory - London, Canada	• Targeted mutation analysis
Maastricht University Medical Centre, Clinical Genomics - Maastricht, Netherlands
Masaryk Hospital - Blood Bank, DNA Laboratory - Usti nad Labem, Czech Republic	• Targeted mutation analysis
Mayo Clinic - Minnesota, Molecular Genetics Laboratory - Rochester, MN, USA	• Targeted mutation analysis
McGill University Health Centre, Molecular Diagnostics - Montreal, Canada	• Targeted mutation analysis
Medgene, MedGene - Bratislava, Slovakia	• Targeted mutation analysis
Mercy St. Vincent Medical Center, Cytogenetics and Molecular Genetics Laboratory - Toledo, OH, USA	• Targeted mutation analysis
MGZ München, Medizinisch Genetisches Zentrum München - München, Germany	• Targeted mutation analysis
Michigan State University, Clinical Genetics Laboratory - East Lansing, MI, USA	• Targeted mutation analysis
MyGen Laboratorio - Madrid, Spain	• Targeted mutation analysis
National University Hospital, Molecular Diagnosis Centre - Department of Laboratory Medicine - Singapore, Singapore	• Targeted mutation analysis
Nebraska Medical Center, Molecular Diagnostic Laboratory - Omaha, NE, USA	• Targeted mutation analysis
North York General Hospital, Molecular Genetics Laboratory - Toronto, Canada	• Targeted mutation analysis
Northwick Park and St. Mark's Hospitals, Kennedy-Galton Centre - NW Thames Regional Genetics Service - Harrow, Great Britain	• Targeted mutation analysis
Nucleo de Genetica Medica de Minas Gerais, GENE - Belo Horizonte, Brazil	• Targeted mutation analysis
Oregon Health and Science University, Knight Diagnostic Laboratories - Molecular Diagnostic Center - Portland, OR, USA	• Targeted mutation analysis
Praxis fuer Humangenetik Wien - Vienna, Austria	• Targeted mutation analysis
Pronto Diagnostics Ltd., ProntoLab - MLPA Lab - Tel Aviv, Israel
Providence Sacred Heart Medical Center and Children's Hospital, Department of Laboratory Medicine/Molecular Diagnostic Division - Spokane, WA, USA	• Targeted mutation analysis
Quest Diagnostics Nichols Institute - California, Molecular Genetics Laboratory - San Juan Capistrano, CA, USA	• Targeted mutation analysis
Quest Diagnostics Nichols Institute - Virginia, Molecular Genetics Laboratory - Chantilly, VA, USA	• Targeted mutation analysis
Research and Innovation - Padova, Italy	• Targeted mutation analysis
Saint Louis University Health Sciences Center, DNA Diagnostic Laboratory - Saint Louis, MO, USA	• Targeted mutation analysis
Seoul National University Hospital, Molecular Diagnostics Laboratory - Seoul, South Korea	• Targeted mutation analysis
Shaare Zedek Medical Center, Medical Genetics Institute - Jerusalem, Israel	• Targeted mutation analysis
Shodair Children's Hospital, Genetics Laboratory - Helena, MT, USA	• Targeted mutation analysis
Sir Ganga Ram Hospital, Center of Medical Genetics - New Delhi, India	• Targeted mutation analysis
Sistemas Genomicos, Medical Genetics Unit - Paterna, Spain	• Targeted mutation analysis
Sunnybrook Health Sciences Centre, Molecular Genetics Laboratory - Toronto, Canada	• Targeted mutation analysis
SUNY Upstate Medical University, Molecular Diagnostic Laboratory - Syracuse, NY, USA	• Targeted mutation analysis
Synlab MVZ Humane Genetik Mnchen, Labor fr Humangenetik - München, Germany	• Targeted mutation analysis
Third Faculty of Medicine, Charles University, Department of Cell and Molecular Biology - Prague, Czech Republic	• Targeted mutation analysis
Tor Vergata University of Roma, School of Medicine, Servizio di Genetica Medica - Rome, Italy	• Targeted mutation analysis
United States Air Force, DNA Diagnostic Laboratory - Keesler AFB, MS, USA	• Targeted mutation analysis
University Health Network, Molecular Diagnostics Laboratory - Toronto, Canada	• Targeted mutation analysis
University Hospital Lausanne, DNA Diagnostic Laboratory - Service de Génétique Médicale - Lausanne, Switzerland	• Targeted mutation analysis
University Hospital of Antwerp, Department of Medical Genetics - Wuyts Lab - Edegem, Belgium	• Targeted mutation analysis
University Hospital of Tuebingen, Medical Genetics Tuebingen - Tuebingen, Germany	• Targeted mutation analysis
University Hospital Ostrava, DNA Diagnostics Laboratory - Ostrava, Czech Republic	• Targeted mutation analysis
University Hospitals - University Hospitals Laboratory Service Foundation, Center for Human Genetics Laboratory - Cleveland, OH, USA	• Targeted mutation analysis
University of Alberta, Molecular Diagnostic Laboratory - Edmonton, Canada	• Targeted mutation analysis
University of California Los Angeles, UCLA Diagnostic Molecular Pathology Laboratory - Los Angeles, CA, USA	• Targeted mutation analysis
University of California, San Francisco, Molecular Diagnostics Laboratory - San Francisco, CA, USA	• Targeted mutation analysis
University of Iowa Hospitals and Clinics, Department of Pathology - Iowa City, IA, USA	• Targeted mutation analysis
University of Kentucky, Immuno-Molecular Pathology - Lexington, KY, USA	• Targeted mutation analysis
University of Michigan, Molecular Diagnostics Laboratory - Ann Arbor, MI, USA	• Targeted mutation analysis
University of Minnesota, University of Minnesota Physicians Outreach Laboratory - Minneapolis, MN, USA	• Targeted mutation analysis
University of North Carolina Hospitals, Molecular Genetics - Chapel Hill, NC, USA	• Targeted mutation analysis
University of Oklahoma Health Sciences Center, Molecular Pathology Laboratory - Oklahoma City, OK, USA	• Targeted mutation analysis
University of Pittsburgh Medical Center, Division of Molecular Diagnostics - Pittsburgh, PA, USA	• Targeted mutation analysis
University of Texas Health Science Center - San Antonio, Molecular Diagnostics Laboratory - San Antonio, TX, USA	• Targeted mutation analysis
University of Virginia Health System, Molecular Diagnostics Laboratory - Charlottesville, VA, USA	• Targeted mutation analysis
Vanderbilt University Medical Center, Molecular Diagnostics Laboratory - Nashville, TN, USA	• Targeted mutation analysis

^* Carrier column is relevant to autosomal recessive and X-linked inheritance; column will be blank when it is not relevant (e.g. autosomal dominant inheritance, microdeletions/duplications) and/or is not offered by the lab.