Disorders

Thyroid Hormone Resistance

Synonym(s): Thyroid Hormone Beta Receptor Deficiency

Gene	Locus	Protein
THRB	3p24.2	Thyroid hormone receptor beta

Laboratory	Test Method	Prenatal	Carrier *
Academic Medical Centre, University of Amsterdam, DNA Diagnostics Laboratory - Amsterdam, Netherlands
Addenbrooke's Hospital, Molecular Genetics Laboratory - Cambridge, Great Britain	• Sequence analysis of select exons
All Children's Hospital, Clinical Molecular Genetics Laboratory - St. Petersburg, FL, USA
bio.logis Center for Human Genetics - Frankfurt, Germany	• Sequence analysis of select exons
Center for Human Genetics, Bioscientia GmbH - Ingelheim, Germany	• Sequence analysis of select exons
Endokrinologikum Hamburg - Center for Hormonal and Metabolic Diseases, Prenatal, and Reproductive Medicine, Molecular Diagnostics - Hamburg, Germany
GENETAQ, Molecular Genetics Centre - Malaga, Spain	• Sequence analysis of select exons
Health Care Center GENOMED, Laboratory of Human Genetics - Warsaw, Poland	• Sequence analysis of select exons
Klinikum Stuttgart, Institute of Clinical Genetics - Stuttgart, Germany
MEDGEN, Genetic Diagnostics Laboratory - Warsaw, Poland	• Sequence analysis of select exons
Medgene, MedGene - Bratislava, Slovakia
Praxis fuer Humangenetik Wien - Vienna, Austria
Quest Diagnostics Nichols Institute - California, Molecular Genetics Laboratory - San Juan Capistrano, CA, USA	• Sequence analysis of select exons

^* Carrier column is relevant to autosomal recessive and X-linked inheritance; column will be blank when it is not relevant (e.g. autosomal dominant inheritance, microdeletions/duplications) and/or is not offered by the lab.