Disorders

Familial Thrombotic Thrombocytopenia Purpura

Gene	Locus	Protein
ADAMTS13	9q34	A disintegrin and metalloproteinase with thrombospondin motifs 13

Laboratory	Test Method	Prenatal	Carrier *
BloodCenter of Wisconsin, Hemostasis Reference Laboratory - Milwaukee, WI, USA	• Protein analysis
Center for Human Genetics, Bioscientia GmbH - Ingelheim, Germany	• Linkage analysis
Center for Nephrology and Metabolic Disorders, Laboratory for Molecular Diagnostics - Weisswasser, Germany
Diagenom GmbH, Medical Genetics Laboratory - Rostock, Germany
GENETAQ, Molecular Genetics Centre - Malaga, Spain
Laboratory for Molecular Diagnostics, Labor-MVZ Westmecklenburg - Schwerin, Germany
PreventionGenetics, Clinical DNA Testing and DNA Banking - Marshfield, WI, USA
Secugen SL - Madrid, Spain

^* Carrier column is relevant to autosomal recessive and X-linked inheritance; column will be blank when it is not relevant (e.g. autosomal dominant inheritance, microdeletions/duplications) and/or is not offered by the lab.