Disorders

Leukocyte Adhesion Deficiency, Type 1

Synonym(s): LAD1, Lymphocyte Function-Associated Antigen 1 Immunodeficiency

Gene	Locus	Protein
ITGB2	21q22.3	Integrin beta-2

Laboratory	Test Method	Prenatal	Carrier *
GeneDx - Gaithersburg, MD, USA
Medgene, MedGene - Bratislava, Slovakia
Praxis fuer Humangenetik Wien - Vienna, Austria
Seattle Children's Research Institute, Immunology Diagnostics Laboratory - Seattle, WA, USA	• Protein expression

^* Carrier column is relevant to autosomal recessive and X-linked inheritance; column will be blank when it is not relevant (e.g. autosomal dominant inheritance, microdeletions/duplications) and/or is not offered by the lab.