Disorders

Gastrointestinal Stromal Tumor

Synonym(s): GIST

Gene	Locus	Protein
PDGFRA	4q12	Platelet-derived growth factor receptor alpha

Laboratory	Test Method	Prenatal	Carrier *
Centogene AG, Rare Disease Company - Rostock, Germany
CGC Genetics - Porto, Portugal	• Sequence analysis of select exons
Diagenom GmbH, Medical Genetics Laboratory - Rostock, Germany	• Sequence analysis of select exons
Dr. Eberhard and Partner, MVZ Dortmund - Dortmund, Germany	• Sequence analysis of select exons
Genetic Diagnosis and Research Center, Genetiks - Istanbul, Turkey	• Sequence analysis of select exons
Laboratory for Molecular Diagnostics, Labor-MVZ Westmecklenburg - Schwerin, Germany	• Sequence analysis of select exons
Manchester St Mary's Hospital, Regional Genetics Laboratories - Manchester, Great Britain
MGZ München, Medizinisch Genetisches Zentrum München - München, Germany
PreventionGenetics, Clinical DNA Testing and DNA Banking - Marshfield, WI, USA
Seoul National University Hospital, Molecular Diagnostics Laboratory - Seoul, South Korea	• Sequence analysis of select exons
Transgenomic, Transgenomic - Omaha - Omaha, NE, USA	• Mutation scanning of select exons

^* Carrier column is relevant to autosomal recessive and X-linked inheritance; column will be blank when it is not relevant (e.g. autosomal dominant inheritance, microdeletions/duplications) and/or is not offered by the lab.