Disorders

Deafness-Dystonia-Optic Neuronopathy Syndrome

Synonym(s): DDON, Deafness-Dystonia Syndrome, DFN 1, DFN1, DFN-1, Jensen syndrome, Mohr-Tranebjaerg Syndrome

Gene	Locus	Protein
TIMM8A	Xq22	Mitochondrial import inner membrane translocase subunit Tim8 A

Laboratory	Test Method	Prenatal	Carrier *
Baylor College of Medicine, Medical Genetics Laboratories - Houston, TX, USA
CeGaT GmbH - Tuebingen, Germany
Centogene AG, Rare Disease Company - Rostock, Germany
Emory University School of Medicine, Emory Molecular Genetics Laboratory - Atlanta, GA, USA
GeneDx - Gaithersburg, MD, USA
General University Hospital in Prague, Institute of Inherited Metabolic Disorders - Praha, Czech Republic
GENETAQ, Molecular Genetics Centre - Malaga, Spain
Medical Neurogenetics - Atlanta, GA, USA
Radboud University Nijmegen Medical Centre, Genome Diagnostics Nijmegen - Nijmegen, Netherlands
University of Copenhagen, Wilhelm Johannsen Centre for Functional Genomics - Copenhagen, Denmark

^* Carrier column is relevant to autosomal recessive and X-linked inheritance; column will be blank when it is not relevant (e.g. autosomal dominant inheritance, microdeletions/duplications) and/or is not offered by the lab.